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Benzocaine has been shown to illicit tonic block of NachBac 9 Equilibrium and biased simulations are used to identify the potential binding sites of these two drugs in the pore, and to quantify the affinity of binding. The other six cases occurred in adult patients who applied the benzocaine gel or liquid to relieve toothache. Once the solution has been injected, it makes the fatty deposits begin to swell.